Inhibition of HMG CoA reductase reveals an unexpected role for cholesterol during PGC migration in the mouse

BACKGROUND: Primordial germ cells (PGCs) are the embryonic precursors of the sperm and eggs. Environmental or genetic defects that alter PGC development can impair fertility or cause formation of germ cell tumors. RESULTS: We demonstrate a novel role for cholesterol during germ cell migration in mic...

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Detalles Bibliográficos
Autores principales: Ding, Jiaxi, Jiang, DeChen, Kurczy, Michael, Nalepka, Jennifer, Dudley, Brian, Merkel, Erin I, Porter, Forbes D, Ewing, Andrew G, Winograd, Nicholas, Burgess, James, Molyneaux, Kathleen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631600/
https://www.ncbi.nlm.nih.gov/pubmed/19117526
http://dx.doi.org/10.1186/1471-213X-8-120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631600/
https://www.ncbi.nlm.nih.gov/pubmed/19117526
http://dx.doi.org/10.1186/1471-213X-8-120

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