Infection with Hepatitis C Virus among HIV-Infected Pregnant Women in Thailand

Objective. The purpose of this study was to describe the epidemiology of coinfection with hepatitis C virus (HCV) and HIV among a cohort of pregnant Thai women. Methods. Samples from 1771 pregnant women enrolled in three vertical transmission of HIV studies in Bangkok, Thailand, were tested for HCV....

Descripción completa

Detalles Bibliográficos
Autores principales: Jamieson, Denise J., Skunodom, Natapakwa, Chaowanachan, Thanyanan, Roongpisuthipong, Anuvat, Bower, William A., Chotpitayasunondh, Tawee, Bhanich Supapol, Wendy, Kuhnert, Wendi L., Siriwasin, Wimol, Wiener, Jeffrey, Chearskul, Sanay, McConnell, Michelle S., Shaffer, Nathan
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631650/
https://www.ncbi.nlm.nih.gov/pubmed/19190779
http://dx.doi.org/10.1155/2008/840948
Descripción
Sumario:Objective. The purpose of this study was to describe the epidemiology of coinfection with hepatitis C virus (HCV) and HIV among a cohort of pregnant Thai women. Methods. Samples from 1771 pregnant women enrolled in three vertical transmission of HIV studies in Bangkok, Thailand, were tested for HCV. Results. Among HIV-infected pregnant women, HCV seroprevelance was 3.8% and the active HCV infection rate was 3.0%. Among HIV-uninfected pregnant women, 0.3% were HCV-infected. Intravenous drug use by the woman was the factor most strongly associated with HCV seropositivity. Among 48 infants tested for HCV who were born to HIV/HCV coinfected women, two infants were HCV infected for an HCV transmission rate of 4.2% (95% 0.51–14.25%). Conclusions. HCV seroprevalence and perinatal transmission rates were low among this Thai cohort of HIV-infected pregnant women.

Ejemplares similares