Clinical characteristics of the West Nile fever outbreak, Israel, 2000.

West Nile (WN) virus is endemic in Israel. The last reported outbreak had occurred in 1981. From August to October 2000, a large-scale epidemic of WN fever occurred in Israel; 417 cases were confirmed, with 326 hospitalizations. The main clinical presentations were encephalitis (57.9%), febrile dise...

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Autores principales: Chowers, M Y, Lang, R, Nassar, F, Ben-David, D, Giladi, M, Rubinshtein, E, Itzhaki, A, Mishal, J, Siegman-Igra, Y, Kitzes, R, Pick, N, Landau, Z, Wolf, D, Bin, H, Mendelson, E, Pitlik, S D, Weinberger, M
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631759/
https://www.ncbi.nlm.nih.gov/pubmed/11585531
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author Chowers, M Y
Lang, R
Nassar, F
Ben-David, D
Giladi, M
Rubinshtein, E
Itzhaki, A
Mishal, J
Siegman-Igra, Y
Kitzes, R
Pick, N
Landau, Z
Wolf, D
Bin, H
Mendelson, E
Pitlik, S D
Weinberger, M
author_facet Chowers, M Y
Lang, R
Nassar, F
Ben-David, D
Giladi, M
Rubinshtein, E
Itzhaki, A
Mishal, J
Siegman-Igra, Y
Kitzes, R
Pick, N
Landau, Z
Wolf, D
Bin, H
Mendelson, E
Pitlik, S D
Weinberger, M
author_sort Chowers, M Y
collection PubMed
description West Nile (WN) virus is endemic in Israel. The last reported outbreak had occurred in 1981. From August to October 2000, a large-scale epidemic of WN fever occurred in Israel; 417 cases were confirmed, with 326 hospitalizations. The main clinical presentations were encephalitis (57.9%), febrile disease (24.4%), and meningitis (15.9%). Within the study group, 33 (14.1%) hospitalized patients died. Mortality was higher among patients >70 years (29.3%). On multivariate regressional analysis, independent predictors of death were age >70 years (odds ratio [OR] 7.7), change in level of consciousness (OR 9.0), and anemia (OR 2.7). In contrast to prior reports, WN fever appears to be a severe illness with high rate of central nervous system involvement and a particularly grim outcome in the elderly.
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spelling pubmed-26317592009-05-20 Clinical characteristics of the West Nile fever outbreak, Israel, 2000. Chowers, M Y Lang, R Nassar, F Ben-David, D Giladi, M Rubinshtein, E Itzhaki, A Mishal, J Siegman-Igra, Y Kitzes, R Pick, N Landau, Z Wolf, D Bin, H Mendelson, E Pitlik, S D Weinberger, M Emerg Infect Dis Research Article West Nile (WN) virus is endemic in Israel. The last reported outbreak had occurred in 1981. From August to October 2000, a large-scale epidemic of WN fever occurred in Israel; 417 cases were confirmed, with 326 hospitalizations. The main clinical presentations were encephalitis (57.9%), febrile disease (24.4%), and meningitis (15.9%). Within the study group, 33 (14.1%) hospitalized patients died. Mortality was higher among patients >70 years (29.3%). On multivariate regressional analysis, independent predictors of death were age >70 years (odds ratio [OR] 7.7), change in level of consciousness (OR 9.0), and anemia (OR 2.7). In contrast to prior reports, WN fever appears to be a severe illness with high rate of central nervous system involvement and a particularly grim outcome in the elderly. Centers for Disease Control and Prevention 2001 /pmc/articles/PMC2631759/ /pubmed/11585531 Text en
spellingShingle Research Article
Chowers, M Y
Lang, R
Nassar, F
Ben-David, D
Giladi, M
Rubinshtein, E
Itzhaki, A
Mishal, J
Siegman-Igra, Y
Kitzes, R
Pick, N
Landau, Z
Wolf, D
Bin, H
Mendelson, E
Pitlik, S D
Weinberger, M
Clinical characteristics of the West Nile fever outbreak, Israel, 2000.
title Clinical characteristics of the West Nile fever outbreak, Israel, 2000.
title_full Clinical characteristics of the West Nile fever outbreak, Israel, 2000.
title_fullStr Clinical characteristics of the West Nile fever outbreak, Israel, 2000.
title_full_unstemmed Clinical characteristics of the West Nile fever outbreak, Israel, 2000.
title_short Clinical characteristics of the West Nile fever outbreak, Israel, 2000.
title_sort clinical characteristics of the west nile fever outbreak, israel, 2000.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631759/
https://www.ncbi.nlm.nih.gov/pubmed/11585531
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