Cargando…

Transcriptional regulation of BRD7 expression by Sp1 and c-Myc

BACKGROUND: Bromodomain is an evolutionally conserved domain that is found in proteins strongly implicated in signal-dependent transcriptional regulation. Genetic alterations of bromodomain genes contributed to the development of many human cancers and other disorders. BRD7 is a recently identified...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Huaying, Zhou, Ming, Luo, Xiaomin, Zhang, Liming, Niu, Zhaoxia, Peng, Cong, Ma, Jian, Peng, Shuping, Zhou, Houde, Xiang, Bo, Li, Xiayu, Li, Shufang, He, Jiajin, Li, Xiaoling, Li, Guiyuan
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632634/ https://www.ncbi.nlm.nih.gov/pubmed/19111069 http://dx.doi.org/10.1186/1471-2199-9-111

Ejemplares similares

Promoter methylation inhibits BRD7 expression in human nasopharyngeal carcinoma cells
por: Liu, Huaying, et al.
Publicado: (2008)

Knockout of BRD7 results in impaired spermatogenesis and male infertility
por: Wang, Heran, et al.
Publicado: (2016)

BRD7 Promotes Cell Proliferation and Tumor Growth Through Stabilization of c-Myc in Colorectal Cancer
por: Zhao, Ran, et al.
Publicado: (2021)

BRD7 expression and c-Myc activation forms a double-negative feedback loop that controls the cell proliferation and tumor growth of nasopharyngeal carcinoma by targeting oncogenic miR-141
por: Liu, Yukun, et al.
Publicado: (2018)

BRD7 suppresses invasion and metastasis in breast cancer by negatively regulating YB1-induced epithelial-mesenchymal transition
por: Niu, Weihong, et al.
Publicado: (2020)

BRD7 Stabilizes P53 via Dephosphorylation of MDM2 to Inhibit Tumor Growth in Breast Cancer Harboring Wild-type P53
por: Luo, Yanwei, et al.
Publicado: (2022)

Disturbing miR-182 and -381 Inhibits BRD7 Transcription and Glioma Growth by Directly Targeting LRRC4
por: Tang, Hailin, et al.
Publicado: (2014)

MiR-200c is a cMyc-activated miRNA that promotes nasopharyngeal carcinoma by downregulating PTEN
por: Chen, Pan, et al.
Publicado: (2016)

BRD7 inhibits the Warburg effect and tumor progression through inactivation of HIF1α/LDHA axis in breast cancer
por: Niu, Weihong, et al.
Publicado: (2018)

Suppression of BRD4 inhibits human hepatocellular carcinoma by repressing MYC and enhancing BIM expression
por: Li, Gong-Quan, et al.
Publicado: (2015)

MYC protein stability is negatively regulated by BRD4
por: Devaiah, Ballachanda N., et al.
Publicado: (2020)

Retraction Note: BRD7 inhibits the Warburg effect and tumor progression through inactivation of HIF1α/LDHA axis in breast cancer
por: Niu, Weihong, et al.
Publicado: (2019)

The BRD4 inhibitor JQ1 suppresses tumor growth by reducing c-Myc expression in endometrial cancer
por: Pang, Yingxin, et al.
Publicado: (2022)

SPLUNC1 Regulates Cell Progression and Apoptosis through the miR-141-PTEN/p27 Pathway, but Is Hindered by LMP1
por: Chen, Pan, et al.
Publicado: (2013)

Signaling Transduction Network Mediated by Tumor Suppressor/Susceptibility Genes in NPC
por: Wu, Minghua, et al.
Publicado: (2009)

Nucleophosmin 1 cooperates with BRD4 to facilitate c-Myc transcription to promote prostate cancer progression
por: Hong, Zhe, et al.
Publicado: (2023)

Epstein-Barr Virus Synergizes with BRD7 to Conquer c-Myc-Mediated Viral Latency Maintenance via Chromatin Remodeling
por: Li, Shen, et al.
Publicado: (2023)

BET inhibitor OTX015 targets BRD2 and BRD4 and decreases c-MYC in acute leukemia cells
por: Coudé, Marie-Magdelaine, et al.
Publicado: (2015)

NEDD4L inhibits cell viability, cell cycle progression, and glutamine metabolism in esophageal squamous cell carcinoma via ubiquitination of c-Myc: NEDD4L and c-Myc coordinate to regulate ESCC
por: Cheng, Wei, et al.
Publicado: (2022)

BRD7 inhibits enhancer activity and expression of BIRC2 to suppress tumor growth and metastasis in nasopharyngeal carcinoma
por: Li, Mengna, et al.
Publicado: (2023)

Bromodomain Protein BRD4-Mediated Mutant p53 Transcription Promotes TNBC Progression
por: Zhou, Julie Xia, et al.
Publicado: (2022)

Berbamine Suppresses the Growth of Gastric Cancer Cells by Inactivating the BRD4/c-MYC Signaling Pathway
por: Li, Hongchun, et al.
Publicado: (2022)

Targeting BRD9 by I-BRD9 efficiently inhibits growth of acute myeloid leukemia cells
por: Zhou, Lixin, et al.
Publicado: (2021)

Egr-1 regulates the transcription of NGX6 gene through a Sp1/Egr-1 overlapping site in the promoter
por: Liu, Minji, et al.
Publicado: (2014)

An inhibitor of BRD4, GNE987, inhibits the growth of glioblastoma cells by targeting C-Myc and S100A16
por: Ma, Liya, et al.
Publicado: (2022)

A natural product targets BRD4 to inhibit phase separation and gene transcription
por: Wang, Cong, et al.
Publicado: (2021)

The effects of MYC on tumor immunity and immunotherapy
por: Li, Jiajin, et al.
Publicado: (2023)

Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism
por: Lu, Huasong, et al.
Publicado: (2015)

GPC6 Promotes Cell Proliferation, Migration, and Invasion in Nasopharyngeal Carcinoma
por: Fan, Chunmei, et al.
Publicado: (2019)

Targeting YAP1/LINC00152/FSCN1 Signaling Axis Prevents the Progression of Colorectal Cancer
por: Ou, Chunlin, et al.
Publicado: (2019)

Cancer stem-like cell: a novel target for nasopharyngeal carcinoma therapy
por: Wei, Pingpin, et al.
Publicado: (2014)

Circulating miR-17, miR-20a, miR-29c, and miR-223 Combined as Non-Invasive Biomarkers in Nasopharyngeal Carcinoma
por: Zeng, Xi, et al.
Publicado: (2012)

HIF-1A and C/EBPs transcriptionally regulate adipogenic differentiation of bone marrow-derived MSCs in hypoxia
por: Jiang, Chen, et al.
Publicado: (2015)

Correction: Compensatory induction of MYC expression by sustained CDK9 inhibition via a BRD4-dependent mechanism
por: Lu, Huasong, et al.
Publicado: (2015)

BRD4 PROTAC degrader ARV-825 inhibits T-cell acute lymphoblastic leukemia by targeting 'Undruggable' Myc-pathway genes
por: Wu, Shuiyan, et al.
Publicado: (2021)

LOC401317, a p53-Regulated Long Non-Coding RNA, Inhibits Cell Proliferation and Induces Apoptosis in the Nasopharyngeal Carcinoma Cell Line HNE2
por: Gong, Zhaojian, et al.
Publicado: (2014)

Recruitment of Brd3 and Brd4 to acetylated chromatin is essential for proinflammatory cytokine-induced matrix-degrading enzyme expression
por: Dai, Jin, et al.
Publicado: (2019)

HMG-box transcription factor 1: a positive regulator of the G1/S transition through the Cyclin-CDK-CDKI molecular network in nasopharyngeal carcinoma
por: He, Shiwei, et al.
Publicado: (2018)

Potent BRD4 inhibitor suppresses cancer cell-macrophage interaction
por: Yin, Mingzhu, et al.
Publicado: (2020)

Targeting bromodomain-containing protein 4 (BRD4) inhibits MYC expression in colorectal cancer cells
por: Otto, C., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_688v19kkshqre18sq66ki746cf