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Substituted trans-stilbenes can inhibit or enhance the TPA-induced up-regulation of activator protein-1
BACKGROUND: The activator protein-1 (AP-1) family of transcription factors contributes to regulation of numerous genes involved in proliferation, apoptosis, and tumorigenesis. A wide array of stimuli can activate AP-1, including pro-inflammatory cytokines, growth factors, tumor promoters and stress....
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632638/ https://www.ncbi.nlm.nih.gov/pubmed/19000313 http://dx.doi.org/10.1186/1471-2210-8-19 |