Large organized chromatin K9-modifications (LOCKs) distinguish differentiated from embryonic stem cells

Higher eukaryotes must adapt a totipotent genome to specialized cell types with a stable but limited repertoire of functions. One potential mechanism for lineage restriction is changes in chromatin, and differentiation-related chromatin changes have been observed for individual genes1–2. We have tak...

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Detalles Bibliográficos
Autores principales: Wen, Bo, Wu, Hao, Shinkai, Yoichi, Irizarry, Rafael A., Feinberg, Andrew P.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632725/
https://www.ncbi.nlm.nih.gov/pubmed/19151716
http://dx.doi.org/10.1038/ng.297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632725/
https://www.ncbi.nlm.nih.gov/pubmed/19151716
http://dx.doi.org/10.1038/ng.297

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