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Large organized chromatin K9-modifications (LOCKs) distinguish differentiated from embryonic stem cells
Higher eukaryotes must adapt a totipotent genome to specialized cell types with a stable but limited repertoire of functions. One potential mechanism for lineage restriction is changes in chromatin, and differentiation-related chromatin changes have been observed for individual genes1–2. We have tak...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632725/ https://www.ncbi.nlm.nih.gov/pubmed/19151716 http://dx.doi.org/10.1038/ng.297 |