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Submicroscopic Gametocytes and the Transmission of Antifolate-Resistant Plasmodium falciparum in Western Kenya

BACKGROUND: Single nucleotide polymorphisms (SNPs) in the dhfr and dhps genes are associated with sulphadoxine-pyrimethamine (SP) treatment failure and gametocyte carriage. This may result in enhanced transmission of mutant malaria parasites, as previously shown for chloroquine resistant parasites....

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Detalles Bibliográficos
Autores principales: Oesterholt, Mayke J. A. M., Alifrangis, Michael, Sutherland, Colin J., Omar, Sabah A., Sawa, Patrick, Howitt, Christina, Gouagna, Louis C., Sauerwein, Robert W., Bousema, Teun
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632751/
https://www.ncbi.nlm.nih.gov/pubmed/19194499
http://dx.doi.org/10.1371/journal.pone.0004364

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