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Disruption of Vps4 and JNK Function in Drosophila Causes Tumour Growth
Several regulators of endocytic trafficking have recently been identified as tumour suppressors in Drosophila. These include components of the endosomal sorting complex required for transport (ESCRT) machinery. Disruption of subunits of ESCRT-I and –II leads to cell-autonomous endosomal accumulation...
Autores principales: | Rodahl, Lina M., Haglund, Kaisa, Sem-Jacobsen, Catherine, Wendler, Franz, Vincent, Jean-Paul, Lindmo, Karine, Rusten, Tor Erik, Stenmark, Harald |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632753/ https://www.ncbi.nlm.nih.gov/pubmed/19194501 http://dx.doi.org/10.1371/journal.pone.0004354 |
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