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Disruption of Vps4 and JNK Function in Drosophila Causes Tumour Growth

Several regulators of endocytic trafficking have recently been identified as tumour suppressors in Drosophila. These include components of the endosomal sorting complex required for transport (ESCRT) machinery. Disruption of subunits of ESCRT-I and –II leads to cell-autonomous endosomal accumulation...

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Detalles Bibliográficos
Autores principales: Rodahl, Lina M., Haglund, Kaisa, Sem-Jacobsen, Catherine, Wendler, Franz, Vincent, Jean-Paul, Lindmo, Karine, Rusten, Tor Erik, Stenmark, Harald
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632753/
https://www.ncbi.nlm.nih.gov/pubmed/19194501
http://dx.doi.org/10.1371/journal.pone.0004354

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