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Detailed Analysis of Sequence Changes Occurring during vlsE Antigenic Variation in the Mouse Model of Borrelia burgdorferi Infection
Lyme disease Borrelia can infect humans and animals for months to years, despite the presence of an active host immune response. The vls antigenic variation system, which expresses the surface-exposed lipoprotein VlsE, plays a major role in B. burgdorferi immune evasion. Gene conversion between vls...
Autores principales: | Coutte, Loïc, Botkin, Douglas J., Gao, Lihui, Norris, Steven J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632889/ https://www.ncbi.nlm.nih.gov/pubmed/19214205 http://dx.doi.org/10.1371/journal.ppat.1000293 |
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