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Physical and functional interaction between DDB and XPA in nucleotide excision repair

Damaged DNA-binding protein (DDB), consisting of DDB1 and DDB2 subunits recognizes a wide spectrum of DNA lesions. DDB is dispensable for in vitro nucleotide excision repair (NER) reaction, but stimulates this reaction especially for cyclobutane pyrimidine dimer (CPD). Here we show that DDB directly...

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Detalles Bibliográficos
Autores principales: Wakasugi, Mitsuo, Kasashima, Hiromi, Fukase, Yuko, Imura, Mayumi, Imai, Rika, Yamada, Saki, Cleaver, James E., Matsunaga, Tsukasa
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632899/
https://www.ncbi.nlm.nih.gov/pubmed/19056823
http://dx.doi.org/10.1093/nar/gkn964

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