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UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells

UHRF1 (ubiquitin-like, containing PHD and RING finger domains 1) is a multi-domain protein associated with cellular proliferation and epigenetic regulation. The UHRF1 binds to methylated CpG dinucleotides and recruits transcriptional repressors DNA methyltransferase 1 (DNMT1) and histone deacetylase...

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Detalles Bibliográficos
Autores principales:	Kim, Jong Kyong, Estève, Pierre-Olivier, Jacobsen, Steven E., Pradhan, Sriharsa
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632929/ https://www.ncbi.nlm.nih.gov/pubmed/19056828 http://dx.doi.org/10.1093/nar/gkn961

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