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Beta amyloid oligomers and fibrils stimulate differential activation of primary microglia
BACKGROUND: Beta amyloid (Aβ) peptides are the major constituents of the senile plaques present in Alzheimer's diseased brain. Pathogenesis has been associated with the aggregated form of the peptide as these fibrils are the conformation readily found in the plaques. However, recent studies hav...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632990/ https://www.ncbi.nlm.nih.gov/pubmed/19123954 http://dx.doi.org/10.1186/1742-2094-6-1 |