When is a GIST not a GIST? A case report of synchronous metastatic gastrointestinal stromal tumor and fibromatosis

BACKGROUND: A number of non-malignant diseases that share similar morphological features as gastrointestinal stromal tumor (GIST) have been reported. Co-existence of GIST with these other diseases is rarely recognized or reported. CASE PRESENTATION: We report a case of a 62 year-old man with long-te...

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Detalles Bibliográficos
Autores principales: Lee, Chee Khoon, Hadley, Alison, Desilva, Keshani, Smith, Gareth, Goldstein, David
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633001/
https://www.ncbi.nlm.nih.gov/pubmed/19159438
http://dx.doi.org/10.1186/1477-7819-7-8
Descripción
Sumario:BACKGROUND: A number of non-malignant diseases that share similar morphological features as gastrointestinal stromal tumor (GIST) have been reported. Co-existence of GIST with these other diseases is rarely recognized or reported. CASE PRESENTATION: We report a case of a 62 year-old man with long-term stable control of metastatic GIST with systemic therapy, presented with an apparent intra-abdominal progression but not supported by imaging with positron emission tomography. Subsequent resection of the intra-abdominal tumor identified a non-malignant fibroid. CONCLUSION: Differentiating localized progression of GIST from other diseases has important prognostic and therapeutic implications. The potential for co-existence of non-malignant soft tissue neoplasm should always be considered.

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