Prominin1 marks intestinal stem cells that are susceptible to neoplastic transformation

Cancer stem cells (CSC) are remarkably similar to normal stem cells: both self-renew, are multipotent and express common surface markers, e.g., PROMININ-1 (PROM1, CD133)1. What remains unclear is whether CSC are the direct progeny of mutated stem cells, or more mature cells that reacquire stem cell...

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Detalles Bibliográficos
Autores principales: Zhu, Liqin, Gibson, Paul, Currle, D. Spencer, Tong, Yiai, Richardson, Robert J., Bayazitov, Ildar T., Poppleton, Helen, Zakharenko, Stanislav, Ellison, David W., Gilbertson, Richard J.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633030/
https://www.ncbi.nlm.nih.gov/pubmed/19092805
http://dx.doi.org/10.1038/nature07589

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