Identification of cyclic peptides able to mimic the functional epitope of IgG1-Fc for human FcγRI

Identification of short, structured peptides able to mimic potently protein-protein interfaces remains a challenge in drug discovery. We report here the use of a naive cyclic peptide phage display library to identify peptide ligands able to recognize and mimic IgG1-Fc functions with FcγRI. Selection...

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Detalles Bibliográficos
Autores principales: Bonetto, Stephane, Spadola, Loredana, Buchanan, Andrew G., Jermutus, Lutz, Lund, John
Formato: Texto
Lenguaje:English
Publicado: The Federation of American Societies for Experimental Biology 2009
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633172/
https://www.ncbi.nlm.nih.gov/pubmed/18957574
http://dx.doi.org/10.1096/fj.08-117069

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