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Systemic Inflammation Induces Acute Behavioral and Cognitive Changes and Accelerates Neurodegenerative Disease

BACKGROUND: Chronic neurodegeneration results in microglial activation, but the contribution of inflammation to the progress of neurodegeneration remains unclear. We have shown that microglia express low levels of proinflammatory cytokines during chronic neurodegeneration but are “primed” to produce...

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Detalles Bibliográficos
Autores principales: Cunningham, Colm, Campion, Suzanne, Lunnon, Katie, Murray, Carol L., Woods, Jack F.C., Deacon, Robert M.J., Rawlins, J. Nicholas P., Perry, V. Hugh
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633437/
https://www.ncbi.nlm.nih.gov/pubmed/18801476
http://dx.doi.org/10.1016/j.biopsych.2008.07.024