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Species-Specific Activity of HIV-1 Vpu and Positive Selection of Tetherin Transmembrane Domain Variants

Tetherin/BST-2/CD317 is a recently identified antiviral protein that blocks the release of nascent retrovirus, and other virus, particles from infected cells. An HIV-1 accessory protein, Vpu, acts as an antagonist of tetherin. Here, we show that positive selection is evident in primate tetherin sequ...

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Detalles Bibliográficos
Autores principales:	McNatt, Matthew W., Zang, Trinity, Hatziioannou, Theodora, Bartlett, Mackenzie, Fofana, Ismael Ben, Johnson, Welkin E., Neil, Stuart J. D., Bieniasz, Paul D.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633611/ https://www.ncbi.nlm.nih.gov/pubmed/19214216 http://dx.doi.org/10.1371/journal.ppat.1000300

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