Transcriptional Profiling in Pathogenic and Non-Pathogenic SIV Infections Reveals Significant Distinctions in Kinetics and Tissue Compartmentalization

Simian immunodeficiency virus (SIV) infection leads to AIDS in experimentally infected macaques, whereas natural reservoir hosts exhibit limited disease and pathology. It is, however, unclear how natural hosts can sustain high viral loads, comparable to those observed in the pathogenic model, withou...

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Detalles Bibliográficos
Autores principales: Lederer, Sharon, Favre, David, Walters, Kathie-Anne, Proll, Sean, Kanwar, Bittoo, Kasakow, Zeljka, Baskin, Carole R., Palermo, Robert, McCune, Joseph M., Katze, Michael G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633618/
https://www.ncbi.nlm.nih.gov/pubmed/19214219
http://dx.doi.org/10.1371/journal.ppat.1000296

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