Chemoselective reduction of aldehydes by ruthenium trichloride and resin-bound formates

A simple, chemoselective transfer hydrogenation of aryl aldehydes with the aid of Amberlite(®) resin formate (ARF), a stable H-donor, in the presence of catalytic ruthenium trichloride is described. Aromatic aldehydes and 1,2-diketones are reduced efficiently and selectively, while aryl ketones rema...

Descripción completa

Detalles Bibliográficos
Autores principales: Basu, Basudeb, Mandal, Bablee, Das, Sajal, Das, Pralay, Nanda, Ashis K
Formato: Texto
Lenguaje:English
Publicado: Beilstein-Institut 2008
Materias:
Preliminary Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633666/
https://www.ncbi.nlm.nih.gov/pubmed/19190744
http://dx.doi.org/10.3762/bjoc.4.53
_version_ 1782164124858318848
author Basu, Basudeb
Mandal, Bablee
Das, Sajal
Das, Pralay
Nanda, Ashis K
author_facet Basu, Basudeb
Mandal, Bablee
Das, Sajal
Das, Pralay
Nanda, Ashis K
author_sort Basu, Basudeb
collection PubMed
description A simple, chemoselective transfer hydrogenation of aryl aldehydes with the aid of Amberlite(®) resin formate (ARF), a stable H-donor, in the presence of catalytic ruthenium trichloride is described. Aromatic aldehydes and 1,2-diketones are reduced efficiently and selectively, while aryl ketones remain unchanged. Several other potentially reducible groups attached to the aromatic moiety are unaffected.
format Text
id pubmed-2633666
institution National Center for Biotechnology Information
language English
publishDate 2008
publisher Beilstein-Institut
record_format MEDLINE/PubMed
spelling pubmed-26336662009-02-02 Chemoselective reduction of aldehydes by ruthenium trichloride and resin-bound formates Basu, Basudeb Mandal, Bablee Das, Sajal Das, Pralay Nanda, Ashis K Beilstein J Org Chem Preliminary Communication A simple, chemoselective transfer hydrogenation of aryl aldehydes with the aid of Amberlite(®) resin formate (ARF), a stable H-donor, in the presence of catalytic ruthenium trichloride is described. Aromatic aldehydes and 1,2-diketones are reduced efficiently and selectively, while aryl ketones remain unchanged. Several other potentially reducible groups attached to the aromatic moiety are unaffected. Beilstein-Institut 2008-12-19 /pmc/articles/PMC2633666/ /pubmed/19190744 http://dx.doi.org/10.3762/bjoc.4.53 Text en Copyright © 2008, Basu et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Preliminary Communication
Basu, Basudeb
Mandal, Bablee
Das, Sajal
Das, Pralay
Nanda, Ashis K
Chemoselective reduction of aldehydes by ruthenium trichloride and resin-bound formates
title Chemoselective reduction of aldehydes by ruthenium trichloride and resin-bound formates
title_full Chemoselective reduction of aldehydes by ruthenium trichloride and resin-bound formates
title_fullStr Chemoselective reduction of aldehydes by ruthenium trichloride and resin-bound formates
title_full_unstemmed Chemoselective reduction of aldehydes by ruthenium trichloride and resin-bound formates
title_short Chemoselective reduction of aldehydes by ruthenium trichloride and resin-bound formates
title_sort chemoselective reduction of aldehydes by ruthenium trichloride and resin-bound formates
topic Preliminary Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633666/
https://www.ncbi.nlm.nih.gov/pubmed/19190744
http://dx.doi.org/10.3762/bjoc.4.53
work_keys_str_mv AT basubasudeb chemoselectivereductionofaldehydesbyrutheniumtrichlorideandresinboundformates
AT mandalbablee chemoselectivereductionofaldehydesbyrutheniumtrichlorideandresinboundformates
AT dassajal chemoselectivereductionofaldehydesbyrutheniumtrichlorideandresinboundformates
AT daspralay chemoselectivereductionofaldehydesbyrutheniumtrichlorideandresinboundformates
AT nandaashisk chemoselectivereductionofaldehydesbyrutheniumtrichlorideandresinboundformates

Ejemplares similares