Human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer

With docetaxel as effective chemotherapy for hormone refractory prostate cancer (HRPC), the number of new treatment combinations for HRPC is expanding demanding a fast-track screening system. This review elaborates on the use of xenograft models to select the most promising combination therapies for...

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Detalles Bibliográficos
Autores principales: van Weerden, W M, Bangma, C, de Wit, R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634688/
https://www.ncbi.nlm.nih.gov/pubmed/19088719
http://dx.doi.org/10.1038/sj.bjc.6604822
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author van Weerden, W M
Bangma, C
de Wit, R
author_facet van Weerden, W M
Bangma, C
de Wit, R
author_sort van Weerden, W M
collection PubMed
description With docetaxel as effective chemotherapy for hormone refractory prostate cancer (HRPC), the number of new treatment combinations for HRPC is expanding demanding a fast-track screening system. This review elaborates on the use of xenograft models to select the most promising combination therapies for entering into phase II clinical trials.
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spelling pubmed-26346882010-01-13 Human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer van Weerden, W M Bangma, C de Wit, R Br J Cancer Review With docetaxel as effective chemotherapy for hormone refractory prostate cancer (HRPC), the number of new treatment combinations for HRPC is expanding demanding a fast-track screening system. This review elaborates on the use of xenograft models to select the most promising combination therapies for entering into phase II clinical trials. Nature Publishing Group 2009-01-13 2008-12-16 /pmc/articles/PMC2634688/ /pubmed/19088719 http://dx.doi.org/10.1038/sj.bjc.6604822 Text en Copyright © 2009 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Review
van Weerden, W M
Bangma, C
de Wit, R
Human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer
title Human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer
title_full Human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer
title_fullStr Human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer
title_full_unstemmed Human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer
title_short Human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer
title_sort human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634688/
https://www.ncbi.nlm.nih.gov/pubmed/19088719
http://dx.doi.org/10.1038/sj.bjc.6604822
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AT dewitr humanxenograftmodelsasusefultoolstoassessthepotentialofnoveltherapeuticsinprostatecancer

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