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The spliceosome as target for anticancer treatment

The spliceosome is a ribonucleoprotein complex involved in RNA splicing, that is, the removal of non-coding introns from precursor messenger RNA. (Alternative) Splicing events may play an essential role in tumourigenesis. The recent discovery that the spliceosome is a target for novel compounds with...

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Detalles Bibliográficos
Autores principales: van Alphen, R J, Wiemer, E A C, Burger, H, Eskens, F A L M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634708/
https://www.ncbi.nlm.nih.gov/pubmed/19034274
http://dx.doi.org/10.1038/sj.bjc.6604801