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The spliceosome as target for anticancer treatment
The spliceosome is a ribonucleoprotein complex involved in RNA splicing, that is, the removal of non-coding introns from precursor messenger RNA. (Alternative) Splicing events may play an essential role in tumourigenesis. The recent discovery that the spliceosome is a target for novel compounds with...
Autores principales: | van Alphen, R J, Wiemer, E A C, Burger, H, Eskens, F A L M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634708/ https://www.ncbi.nlm.nih.gov/pubmed/19034274 http://dx.doi.org/10.1038/sj.bjc.6604801 |
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