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RASSF1A hypermethylation in pretreatment serum DNA of neuroblastoma patients: a prognostic marker

The tumour suppressor gene RASSF1A is known to be frequently silenced by promoter hypermethylation in neuroblastoma tumours. Here we explored the possible prognostic significance of aberrant promoter hypermethylation of RASSF1A in serum DNA samples of patients with neuroblastoma as a surrogate marke...

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Detalles Bibliográficos
Autores principales: Misawa, A, Tanaka, S, Yagyu, S, Tsuchiya, K, Iehara, T, Sugimoto, T, Hosoi, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634715/
https://www.ncbi.nlm.nih.gov/pubmed/19165202
http://dx.doi.org/10.1038/sj.bjc.6604887