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RASSF1A hypermethylation in pretreatment serum DNA of neuroblastoma patients: a prognostic marker
The tumour suppressor gene RASSF1A is known to be frequently silenced by promoter hypermethylation in neuroblastoma tumours. Here we explored the possible prognostic significance of aberrant promoter hypermethylation of RASSF1A in serum DNA samples of patients with neuroblastoma as a surrogate marke...
Autores principales: | Misawa, A, Tanaka, S, Yagyu, S, Tsuchiya, K, Iehara, T, Sugimoto, T, Hosoi, H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634715/ https://www.ncbi.nlm.nih.gov/pubmed/19165202 http://dx.doi.org/10.1038/sj.bjc.6604887 |
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