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Folate and colorectal cancer prevention

Anti-folate chemotherapy agents such as methotrexate and fluorouracil reduce proliferation of neoplastic cells by inhibiting DNA synthesis. Paradoxically epidemiological data suggests an inverse relationship between dietary folate intake and incidence of colorectal cancer (CRC). On the basis of this...

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Detalles Bibliográficos
Autores principales:	Hubner, R A, Houlston, R S
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634716/ https://www.ncbi.nlm.nih.gov/pubmed/19088716 http://dx.doi.org/10.1038/sj.bjc.6604823

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