A recurrent truncating germline mutation in the BRIP1/FANCJ gene and susceptibility to prostate cancer

Although prostate cancer (PrCa) is one of the most common cancers in men in Western countries, little is known about the inherited factors that influence PrCa risk. On the basis of the fact that BRIP1/FANCJ interacts with BRCA1 and functions as a regulator of DNA double-strand break repair pathways,...

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Detalles Bibliográficos
Autores principales: Kote-Jarai, Z, Jugurnauth, S, Mulholland, S, Leongamornlert, D A, Guy, M, Edwards, S, Tymrakiewitcz, M, O'Brien, L, Hall, A, Wilkinson, R, Al Olama, A A, Morrison, J, Muir, K, Neal, D, Donovan, J, Hamdy, F, Easton, D F, Eeles, R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634720/
https://www.ncbi.nlm.nih.gov/pubmed/19127258
http://dx.doi.org/10.1038/sj.bjc.6604847

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