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Direct effects of doxorubicin on skeletal muscle contribute to fatigue
Chemotherapy-induced fatigue is a multidimensional symptom. Oxidative stress has been proposed as a working mechanism for anthracycline-induced cardiotoxicity. In this study, doxorubicin (DOX) was tested on skeletal muscle function. Doxorubicin induced impaired ex vivo skeletal muscle relaxation fol...
Autores principales: | van Norren, K, van Helvoort, A, Argilés, J M, van Tuijl, S, Arts, Karin, Gorselink, M, Laviano, A, Kegler, D, Haagsman, H P, van der Beek, E M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634729/ https://www.ncbi.nlm.nih.gov/pubmed/19165199 http://dx.doi.org/10.1038/sj.bjc.6604858 |
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