Mutation Patterns in the Human Genome: More Variable Than Expected

Why are some genomic positions more mutable than others? The identification of cryptic mutation hotspots in the human genome indicates that the determinants of mutation rates are more complex than anticipated.

Detalles Bibliográficos
Autor principal: Duret, Laurent
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Primer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634789/
https://www.ncbi.nlm.nih.gov/pubmed/19192948
http://dx.doi.org/10.1371/journal.pbio.1000028
Descripción
Sumario:Why are some genomic positions more mutable than others? The identification of cryptic mutation hotspots in the human genome indicates that the determinants of mutation rates are more complex than anticipated.

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