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Antiproliferative Effect of Ascorbic Acid Is Associated with the Inhibition of Genes Necessary to Cell Cycle Progression
BACKGROUND: Ascorbic acid (AA), or Vitamin C, is most well known as a nutritional supplement with antioxidant properties. Recently, we demonstrated that high concentrations of AA act on PMP22 gene expression and partially correct the Charcot-Marie-Tooth disease phenotype in a mouse model. This is du...
Autores principales: | Belin, Sophie, Kaya, Ferdinand, Duisit, Ghislaine, Giacometti, Sarah, Ciccolini, Joseph, Fontés, Michel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634969/ https://www.ncbi.nlm.nih.gov/pubmed/19197388 http://dx.doi.org/10.1371/journal.pone.0004409 |
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