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Antiproliferative Effect of Ascorbic Acid Is Associated with the Inhibition of Genes Necessary to Cell Cycle Progression

BACKGROUND: Ascorbic acid (AA), or Vitamin C, is most well known as a nutritional supplement with antioxidant properties. Recently, we demonstrated that high concentrations of AA act on PMP22 gene expression and partially correct the Charcot-Marie-Tooth disease phenotype in a mouse model. This is du...

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Detalles Bibliográficos
Autores principales: Belin, Sophie, Kaya, Ferdinand, Duisit, Ghislaine, Giacometti, Sarah, Ciccolini, Joseph, Fontés, Michel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634969/
https://www.ncbi.nlm.nih.gov/pubmed/19197388
http://dx.doi.org/10.1371/journal.pone.0004409

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