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Rapid Mutation of Endogenous Zebrafish Genes Using Zinc Finger Nucleases Made by Oligomerized Pool ENgineering (OPEN)

BACKGROUND: Customized zinc finger nucleases (ZFNs) form the basis of a broadly applicable tool for highly efficient genome modification. ZFNs are artificial restriction endonucleases consisting of a non-specific nuclease domain fused to a zinc finger array which can be engineered to recognize speci...

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Detalles Bibliográficos
Autores principales:	Foley, Jonathan E., Yeh, Jing-Ruey J., Maeder, Morgan L., Reyon, Deepak, Sander, Jeffry D., Peterson, Randall T., Joung, J. Keith
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634973/ https://www.ncbi.nlm.nih.gov/pubmed/19198653 http://dx.doi.org/10.1371/journal.pone.0004348

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