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Significance of the parkin and PINK1 gene in Jordanian families with incidences of young-onset and juvenile parkinsonism

BACKGROUND: Parkinson's disease is a progressive neurodegenerative disorder, where most cases are sporadic with a late onset. In rare incidences familial forms of early-onset parkinsonism occur, and when recessively inherited, cases are often explained by mutations in either the parkin (PARK2)...

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Detalles Bibliográficos
Autores principales: Myhre, Ronny, Steinkjer, Stina, Stormyr, Alice, Nilsen, Gina L, Zayyad, Hiba Abu, Horany, Khalid, Nusier, Mohamad K, Klungland, Helge
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635385/
https://www.ncbi.nlm.nih.gov/pubmed/19087301
http://dx.doi.org/10.1186/1471-2377-8-47