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A Comparative Chemogenomics Strategy to Predict Potential Drug Targets in the Metazoan Pathogen, Schistosoma mansoni

Schistosomiasis is a prevalent and chronic helmintic disease in tropical regions. Treatment and control relies on chemotherapy with just one drug, praziquantel and this reliance is of concern should clinically relevant drug resistance emerge and spread. Therefore, to identify potential target protei...

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Detalles Bibliográficos
Autores principales: Caffrey, Conor R., Rohwer, Andreas, Oellien, Frank, Marhöfer, Richard J., Braschi, Simon, Oliveira, Guilherme, McKerrow, James H., Selzer, Paul M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635471/
https://www.ncbi.nlm.nih.gov/pubmed/19198654
http://dx.doi.org/10.1371/journal.pone.0004413