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A Comparative Chemogenomics Strategy to Predict Potential Drug Targets in the Metazoan Pathogen, Schistosoma mansoni
Schistosomiasis is a prevalent and chronic helmintic disease in tropical regions. Treatment and control relies on chemotherapy with just one drug, praziquantel and this reliance is of concern should clinically relevant drug resistance emerge and spread. Therefore, to identify potential target protei...
Autores principales: | Caffrey, Conor R., Rohwer, Andreas, Oellien, Frank, Marhöfer, Richard J., Braschi, Simon, Oliveira, Guilherme, McKerrow, James H., Selzer, Paul M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635471/ https://www.ncbi.nlm.nih.gov/pubmed/19198654 http://dx.doi.org/10.1371/journal.pone.0004413 |
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