Pegaptanib sodium for ocular vascular disease

Pegaptanib sodium (Macugen(TM)) is a selective RNA aptamer that inhibits vascular endothelial growth factor (VEGF)( 165) , the VEGF isoform primarily responsible for pathologic ocular neovascularization and vascular permeability, while sparing the physiological isoform VEGF( 121) . After more than 1...

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Detalles Bibliográficos
Autores principales: Shukla, Dhananjay, Namperumalsamy, Perumalsamy, Goldbaum, Mauro, Cunningham Jr, Emmett T
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2007
Materias:
Symposium
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635976/
https://www.ncbi.nlm.nih.gov/pubmed/17951898

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