Voriconazole for the treatment of refractory Aspergillus fumigatus keratitis

We report a case of Aspergillus fumigatus keratitis in a 53-year-old, well-controlled diabetic female who did not respond to standard antifungal treatment. She was started on topical natamycin eye drops, but the infiltrate continued to progress. Topical amphotericin B and systemic ketoconazole was a...

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Detalles Bibliográficos
Autores principales: Mehta, Hijab, Mehta, Hitendra B, Garg, Prashant, Kodial, Harish
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2008
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636104/
https://www.ncbi.nlm.nih.gov/pubmed/18417831
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author Mehta, Hijab
Mehta, Hitendra B
Garg, Prashant
Kodial, Harish
author_facet Mehta, Hijab
Mehta, Hitendra B
Garg, Prashant
Kodial, Harish
author_sort Mehta, Hijab
collection PubMed
description We report a case of Aspergillus fumigatus keratitis in a 53-year-old, well-controlled diabetic female who did not respond to standard antifungal treatment. She was started on topical natamycin eye drops, but the infiltrate continued to progress. Topical amphotericin B and systemic ketoconazole was added, however, there was no response and the infiltrate increased further. She was then switched to topical and systemic voriconazole. Steady resolution of the infiltrate was noted within 2 weeks of therapy.
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spelling pubmed-26361042009-02-10 Voriconazole for the treatment of refractory Aspergillus fumigatus keratitis Mehta, Hijab Mehta, Hitendra B Garg, Prashant Kodial, Harish Indian J Ophthalmol Brief Communication We report a case of Aspergillus fumigatus keratitis in a 53-year-old, well-controlled diabetic female who did not respond to standard antifungal treatment. She was started on topical natamycin eye drops, but the infiltrate continued to progress. Topical amphotericin B and systemic ketoconazole was added, however, there was no response and the infiltrate increased further. She was then switched to topical and systemic voriconazole. Steady resolution of the infiltrate was noted within 2 weeks of therapy. Medknow Publications 2008 /pmc/articles/PMC2636104/ /pubmed/18417831 Text en Copyright: © Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communication
Mehta, Hijab
Mehta, Hitendra B
Garg, Prashant
Kodial, Harish
Voriconazole for the treatment of refractory Aspergillus fumigatus keratitis
title Voriconazole for the treatment of refractory Aspergillus fumigatus keratitis
title_full Voriconazole for the treatment of refractory Aspergillus fumigatus keratitis
title_fullStr Voriconazole for the treatment of refractory Aspergillus fumigatus keratitis
title_full_unstemmed Voriconazole for the treatment of refractory Aspergillus fumigatus keratitis
title_short Voriconazole for the treatment of refractory Aspergillus fumigatus keratitis
title_sort voriconazole for the treatment of refractory aspergillus fumigatus keratitis
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636104/
https://www.ncbi.nlm.nih.gov/pubmed/18417831
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AT kodialharish voriconazoleforthetreatmentofrefractoryaspergillusfumigatuskeratitis

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