Neurotrophic keratitis in a patient with dihydroxypyrimidine dehydrogenase deficiency

We describe a case of neurotrophic keratitis in association with dihydroxypyrimidine dehydrogenase (DHPD) deficiency. Ocular manifestations in patients with DHPD are rare and neurotrophic keratitis has never been reported before. A six-year- old boy who was a known case of DHPD deficiency and born o...

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Autores principales: Kapoor, Bharat, Luhishi, Ezzedin A, Chung, Andrew K K, Pauw, Jakobus C
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2008
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636154/
https://www.ncbi.nlm.nih.gov/pubmed/18580000
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author Kapoor, Bharat
Luhishi, Ezzedin A
Chung, Andrew K K
Pauw, Jakobus C
author_facet Kapoor, Bharat
Luhishi, Ezzedin A
Chung, Andrew K K
Pauw, Jakobus C
author_sort Kapoor, Bharat
collection PubMed
description We describe a case of neurotrophic keratitis in association with dihydroxypyrimidine dehydrogenase (DHPD) deficiency. Ocular manifestations in patients with DHPD are rare and neurotrophic keratitis has never been reported before. A six-year- old boy who was a known case of DHPD deficiency and born of a consanguineous marriage presented to our clinic with non- healing corneal ulcers in both eyes. Reduced corneal sensations were detected and the patient was started on lubricating eye drops. The patient continues to be on lubricant eye drops and there has been no recurrence of the disease.
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spelling pubmed-26361542009-02-10 Neurotrophic keratitis in a patient with dihydroxypyrimidine dehydrogenase deficiency Kapoor, Bharat Luhishi, Ezzedin A Chung, Andrew K K Pauw, Jakobus C Indian J Ophthalmol Brief Communication We describe a case of neurotrophic keratitis in association with dihydroxypyrimidine dehydrogenase (DHPD) deficiency. Ocular manifestations in patients with DHPD are rare and neurotrophic keratitis has never been reported before. A six-year- old boy who was a known case of DHPD deficiency and born of a consanguineous marriage presented to our clinic with non- healing corneal ulcers in both eyes. Reduced corneal sensations were detected and the patient was started on lubricating eye drops. The patient continues to be on lubricant eye drops and there has been no recurrence of the disease. Medknow Publications 2008 /pmc/articles/PMC2636154/ /pubmed/18580000 Text en Copyright: © Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communication
Kapoor, Bharat
Luhishi, Ezzedin A
Chung, Andrew K K
Pauw, Jakobus C
Neurotrophic keratitis in a patient with dihydroxypyrimidine dehydrogenase deficiency
title Neurotrophic keratitis in a patient with dihydroxypyrimidine dehydrogenase deficiency
title_full Neurotrophic keratitis in a patient with dihydroxypyrimidine dehydrogenase deficiency
title_fullStr Neurotrophic keratitis in a patient with dihydroxypyrimidine dehydrogenase deficiency
title_full_unstemmed Neurotrophic keratitis in a patient with dihydroxypyrimidine dehydrogenase deficiency
title_short Neurotrophic keratitis in a patient with dihydroxypyrimidine dehydrogenase deficiency
title_sort neurotrophic keratitis in a patient with dihydroxypyrimidine dehydrogenase deficiency
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636154/
https://www.ncbi.nlm.nih.gov/pubmed/18580000
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AT luhishiezzedina neurotrophickeratitisinapatientwithdihydroxypyrimidinedehydrogenasedeficiency
AT chungandrewkk neurotrophickeratitisinapatientwithdihydroxypyrimidinedehydrogenasedeficiency
AT pauwjakobusc neurotrophickeratitisinapatientwithdihydroxypyrimidinedehydrogenasedeficiency

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