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A Drosophila Model for EGFR-Ras and PI3K-Dependent Human Glioma

Gliomas, the most common malignant tumors of the nervous system, frequently harbor mutations that activate the epidermal growth factor receptor (EGFR) and phosphatidylinositol-3 kinase (PI3K) signaling pathways. To investigate the genetic basis of this disease, we developed a glioma model in Drosoph...

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Detalles Bibliográficos
Autores principales: Read, Renee D., Cavenee, Webster K., Furnari, Frank B., Thomas, John B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636203/
https://www.ncbi.nlm.nih.gov/pubmed/19214224
http://dx.doi.org/10.1371/journal.pgen.1000374

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