Reversible pH-controlled DNA-binding peptide nanotweezers: An in-silico study

We describe the molecular dynamics (MD)-aided engineering design of mutant peptides based on the α-helical coiled-coil GCN4 leucine zipper peptide (GCN4-p1) in order to obtain environmentally-responsive nanotweezers. The actuation mechanism of the nanotweezers depends on the modification of electros...

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Detalles Bibliográficos
Autores principales: Sharma, Gaurav, Rege, Kaushal, Budil, David E, Yarmush, Martin L, Mavroidis, Constantinos
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2008
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636583/
https://www.ncbi.nlm.nih.gov/pubmed/19337419

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