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Removal of cell surface heparan sulfate increases TACE activity and cleavage of ErbB4 receptor
BACKGROUND: Nuclear localization of proteolytically formed intracellular fragment of ErbB4 receptor tyrosine kinase has been shown to promote cell survival, and nuclear localization of ErbB4 receptor has been described in human breast cancer. Tumor necrosis factor alpha converting enzyme (TACE) init...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636757/ https://www.ncbi.nlm.nih.gov/pubmed/19171023 http://dx.doi.org/10.1186/1471-2121-10-5 |