Cargando…

Genome Projector: zoomable genome map with multiple views

BACKGROUND: Molecular biology data exist on diverse scales, from the level of molecules to -omics. At the same time, the data at each scale can be categorised into multiple layers, such as the genome, transcriptome, proteome, metabolome, and biochemical pathways. Due to the highly multi-layer and mu...

Descripción completa

Detalles Bibliográficos
Autores principales: Arakawa, Kazuharu, Tamaki, Satoshi, Kono, Nobuaki, Kido, Nobuhiro, Ikegami, Keita, Ogawa, Ryu, Tomita, Masaru
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636772/
https://www.ncbi.nlm.nih.gov/pubmed/19166610
http://dx.doi.org/10.1186/1471-2105-10-31
_version_ 1782164302176714752
author Arakawa, Kazuharu
Tamaki, Satoshi
Kono, Nobuaki
Kido, Nobuhiro
Ikegami, Keita
Ogawa, Ryu
Tomita, Masaru
author_facet Arakawa, Kazuharu
Tamaki, Satoshi
Kono, Nobuaki
Kido, Nobuhiro
Ikegami, Keita
Ogawa, Ryu
Tomita, Masaru
author_sort Arakawa, Kazuharu
collection PubMed
description BACKGROUND: Molecular biology data exist on diverse scales, from the level of molecules to -omics. At the same time, the data at each scale can be categorised into multiple layers, such as the genome, transcriptome, proteome, metabolome, and biochemical pathways. Due to the highly multi-layer and multi-dimensional nature of biological information, software interfaces for database browsing should provide an intuitive interface that allows for rapid migration across different views and scales. The Zoomable User Interface (ZUI) and tabbed browsing have proven successful for this purpose in other areas, especially to navigate the vast information in the World Wide Web. RESULTS: This paper presents Genome Projector, a Web-based gateway for genomics information with a zoomable user interface using Google Maps API, equipped with four seamlessly accessible and searchable views: a circular genome map, a traditional genome map, a biochemical pathways map, and a DNA walk map. The Web application for 320 bacterial genomes is available at . All data and software including the source code, documentations, and development API are freely available under the GNU General Public License. Zoomable maps can be easily created from any image file using the development API, and an online data mapping service for Genome Projector is also available at our Web site. CONCLUSION: Genome Projector is an intuitive Web application for browsing genomics information, implemented with a zoomable user interface and tabbed browsing utilising Google Maps API and Asynchronous JavaScript and XML (AJAX) technology.
format Text
id pubmed-2636772
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-26367722009-02-06 Genome Projector: zoomable genome map with multiple views Arakawa, Kazuharu Tamaki, Satoshi Kono, Nobuaki Kido, Nobuhiro Ikegami, Keita Ogawa, Ryu Tomita, Masaru BMC Bioinformatics Software BACKGROUND: Molecular biology data exist on diverse scales, from the level of molecules to -omics. At the same time, the data at each scale can be categorised into multiple layers, such as the genome, transcriptome, proteome, metabolome, and biochemical pathways. Due to the highly multi-layer and multi-dimensional nature of biological information, software interfaces for database browsing should provide an intuitive interface that allows for rapid migration across different views and scales. The Zoomable User Interface (ZUI) and tabbed browsing have proven successful for this purpose in other areas, especially to navigate the vast information in the World Wide Web. RESULTS: This paper presents Genome Projector, a Web-based gateway for genomics information with a zoomable user interface using Google Maps API, equipped with four seamlessly accessible and searchable views: a circular genome map, a traditional genome map, a biochemical pathways map, and a DNA walk map. The Web application for 320 bacterial genomes is available at . All data and software including the source code, documentations, and development API are freely available under the GNU General Public License. Zoomable maps can be easily created from any image file using the development API, and an online data mapping service for Genome Projector is also available at our Web site. CONCLUSION: Genome Projector is an intuitive Web application for browsing genomics information, implemented with a zoomable user interface and tabbed browsing utilising Google Maps API and Asynchronous JavaScript and XML (AJAX) technology. BioMed Central 2009-01-23 /pmc/articles/PMC2636772/ /pubmed/19166610 http://dx.doi.org/10.1186/1471-2105-10-31 Text en Copyright © 2009 Arakawa et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Software
Arakawa, Kazuharu
Tamaki, Satoshi
Kono, Nobuaki
Kido, Nobuhiro
Ikegami, Keita
Ogawa, Ryu
Tomita, Masaru
Genome Projector: zoomable genome map with multiple views
title Genome Projector: zoomable genome map with multiple views
title_full Genome Projector: zoomable genome map with multiple views
title_fullStr Genome Projector: zoomable genome map with multiple views
title_full_unstemmed Genome Projector: zoomable genome map with multiple views
title_short Genome Projector: zoomable genome map with multiple views
title_sort genome projector: zoomable genome map with multiple views
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636772/
https://www.ncbi.nlm.nih.gov/pubmed/19166610
http://dx.doi.org/10.1186/1471-2105-10-31
work_keys_str_mv AT arakawakazuharu genomeprojectorzoomablegenomemapwithmultipleviews
AT tamakisatoshi genomeprojectorzoomablegenomemapwithmultipleviews
AT kononobuaki genomeprojectorzoomablegenomemapwithmultipleviews
AT kidonobuhiro genomeprojectorzoomablegenomemapwithmultipleviews
AT ikegamikeita genomeprojectorzoomablegenomemapwithmultipleviews
AT ogawaryu genomeprojectorzoomablegenomemapwithmultipleviews
AT tomitamasaru genomeprojectorzoomablegenomemapwithmultipleviews