A new 500 kb haplotype associated with high CD8+ T-lymphocyte numbers predicts a less severe expression of hereditary hemochromatosis

BACKGROUND: Hereditary Hemochromatosis(HH) is a common genetic disorder of iron overload where the large majority of patients are homozygous for one ancestral mutation in the HFE gene. In spite of this remarkable genetic homogeneity, the condition is clinically heterogeneous, varying from a severe d...

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Detalles Bibliográficos
Autores principales: Cruz, Eugénia, Whittington, Chris, Krikler, Samuel H, Mascarenhas, Cláudia, Lacerda, Rosa, Vieira, Jorge, Porto, Graça
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636778/
https://www.ncbi.nlm.nih.gov/pubmed/18990219
http://dx.doi.org/10.1186/1471-2350-9-97

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