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Trends in hospitalizations for diagnosed congenital cytomegalovirus in infants and children in Australia

BACKGROUND: Cytomegalovirus (CMV) is responsible for a wide range of diseases in neonates, and has been recognized as a major cause of congenital defects in developed countries for many years. More children suffer serious disabilities caused by congenital CMV than by several better-known childhood m...

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Autores principales: Seale, Holly, Booy, Robert, MacIntyre, C Raina
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636807/
https://www.ncbi.nlm.nih.gov/pubmed/19171068
http://dx.doi.org/10.1186/1471-2431-9-7
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author Seale, Holly
Booy, Robert
MacIntyre, C Raina
author_facet Seale, Holly
Booy, Robert
MacIntyre, C Raina
author_sort Seale, Holly
collection PubMed
description BACKGROUND: Cytomegalovirus (CMV) is responsible for a wide range of diseases in neonates, and has been recognized as a major cause of congenital defects in developed countries for many years. More children suffer serious disabilities caused by congenital CMV than by several better-known childhood maladies. Insight into the epidemiology of congenital CMV disease is needed for the assessment of preventive strategies. METHODS: Using data from the National Hospital Morbidity Database (NHMD) complied by the Australian Institute of Health and Welfare (AIHW), we examined the rates of hospital admissions for children diagnosed with congenital cytomegalovirus (CMV) by year, sex, age group and length of stay. RESULTS: Over an 8-year period (1993–2001), there were 1314 admissions for the congenital form of CMV disease. Of these admissions, 25% were principally hospitalized because of congenital CMV. The average annual rate of admissions in children aged 0–4, 5–9 and 10–14 years was 9.40, 2.40 and 0.85 per 100,000 Australian population respectively. CONCLUSION: Compared with many other congenital illnesses, which are now vaccine preventable, the burden of congenital CMV is comparatively high. A vaccination program would be justifiable should a vaccine become available.
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spelling pubmed-26368072009-02-06 Trends in hospitalizations for diagnosed congenital cytomegalovirus in infants and children in Australia Seale, Holly Booy, Robert MacIntyre, C Raina BMC Pediatr Research Article BACKGROUND: Cytomegalovirus (CMV) is responsible for a wide range of diseases in neonates, and has been recognized as a major cause of congenital defects in developed countries for many years. More children suffer serious disabilities caused by congenital CMV than by several better-known childhood maladies. Insight into the epidemiology of congenital CMV disease is needed for the assessment of preventive strategies. METHODS: Using data from the National Hospital Morbidity Database (NHMD) complied by the Australian Institute of Health and Welfare (AIHW), we examined the rates of hospital admissions for children diagnosed with congenital cytomegalovirus (CMV) by year, sex, age group and length of stay. RESULTS: Over an 8-year period (1993–2001), there were 1314 admissions for the congenital form of CMV disease. Of these admissions, 25% were principally hospitalized because of congenital CMV. The average annual rate of admissions in children aged 0–4, 5–9 and 10–14 years was 9.40, 2.40 and 0.85 per 100,000 Australian population respectively. CONCLUSION: Compared with many other congenital illnesses, which are now vaccine preventable, the burden of congenital CMV is comparatively high. A vaccination program would be justifiable should a vaccine become available. BioMed Central 2009-01-26 /pmc/articles/PMC2636807/ /pubmed/19171068 http://dx.doi.org/10.1186/1471-2431-9-7 Text en Copyright © 2009 Seale et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Seale, Holly
Booy, Robert
MacIntyre, C Raina
Trends in hospitalizations for diagnosed congenital cytomegalovirus in infants and children in Australia
title Trends in hospitalizations for diagnosed congenital cytomegalovirus in infants and children in Australia
title_full Trends in hospitalizations for diagnosed congenital cytomegalovirus in infants and children in Australia
title_fullStr Trends in hospitalizations for diagnosed congenital cytomegalovirus in infants and children in Australia
title_full_unstemmed Trends in hospitalizations for diagnosed congenital cytomegalovirus in infants and children in Australia
title_short Trends in hospitalizations for diagnosed congenital cytomegalovirus in infants and children in Australia
title_sort trends in hospitalizations for diagnosed congenital cytomegalovirus in infants and children in australia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636807/
https://www.ncbi.nlm.nih.gov/pubmed/19171068
http://dx.doi.org/10.1186/1471-2431-9-7
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