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Preserved glucose tolerance in high-fat-fed C57BL/6 mice transplanted with PPARγ(−/−), PPARδ(−/−), PPARγδ(−/−), or LXRαβ(−/−) bone marrow
Macrophage lipid metabolism and inflammatory responses are both regulated by the nuclear receptors PPAR and LXR. Emerging links between inflammation and metabolic disease progression suggest that PPAR and LXR signaling may alter macrophage function and thereby impact systemic metabolism. In this stu...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636915/ https://www.ncbi.nlm.nih.gov/pubmed/18772483 http://dx.doi.org/10.1194/jlr.M800189-JLR200 |