Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia

Liver X receptors (LXRs) are important regulators of cholesterol and lipid metabolism. LXR agonists have been shown to limit the cellular cholesterol content by inducing reverse cholesterol transport, increasing bile acid production, and inhibiting intestinal cholesterol absorption. Most of them, ho...

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Detalles Bibliográficos
Autores principales: Kratzer, Adelheid, Buchebner, Marlene, Pfeifer, Thomas, Becker, Tatjana M., Uray, Georg, Miyazaki, Makoto, Miyazaki-Anzai, Shinobu, Ebner, Birgit, Chandak, Prakash G., Kadam, Rajendra S., Calayir, Emine, Rathke, Nora, Ahammer, Helmut, Radovic, Branislav, Trauner, Michael, Hoefler, Gerald, Kompella, Uday B., Fauler, Guenter, Levi, Moshe, Levak-Frank, Sanja, Kostner, Gerhard M., Kratky, Dagmar
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636920/
https://www.ncbi.nlm.nih.gov/pubmed/18812595
http://dx.doi.org/10.1194/jlr.M800376-JLR200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636920/
https://www.ncbi.nlm.nih.gov/pubmed/18812595
http://dx.doi.org/10.1194/jlr.M800376-JLR200

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