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HIV-1 coreceptor usage prediction without multiple alignments: an application of string kernels

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) infects cells by means of ligand-receptor interactions. This lentivirus uses the CD4 receptor in conjunction with a chemokine coreceptor, either CXCR4 or CCR5, to enter a target cell. HIV-1 is characterized by high sequence variability. Nonethe...

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Detalles Bibliográficos
Autores principales:	Boisvert, Sébastien, Marchand, Mario, Laviolette, François, Corbeil, Jacques
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637298/ https://www.ncbi.nlm.nih.gov/pubmed/19055831 http://dx.doi.org/10.1186/1742-4690-5-110

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