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Genetic and other factors determining mannose-binding lectin levels in American Indians: the Strong Heart Study

BACKGROUND: Mannose-binding lectin (MBL) forms an integral part of the innate immune system. Persistent, subclinical infections and chronic inflammatory states are hypothesized to contribute to the pathogenesis of atherosclerosis. MBL gene (MBL2) variants with between 12 to 25% allele frequency in C...

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Detalles Bibliográficos
Autores principales: Best, Lyle G, Ferrell, Robert E, DeCroo, Susan, North, Kari E, MacCluer, Jean W, Zhang, Ying, Lee, Elisa T, Howard, Barbara V, Umans, Jason, Palmieri, Vittorio, Garred, Peter
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637849/
https://www.ncbi.nlm.nih.gov/pubmed/19161617
http://dx.doi.org/10.1186/1471-2350-10-5