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Increased PADI4 expression in blood and tissues of patients with malignant tumors

BACKGROUND: Peptidylarginine deiminase type 4 (PAD4/PADI4) post-translationally converts peptidylarginine to citrulline. Recent studies suggest that PADI4 represses expression of p53-regulated genes via citrullination of histones at gene promoters. METHODS: Expression of PADI4 was investigated in va...

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Detalles Bibliográficos
Autores principales: Chang, Xiaotian, Han, Jinxiang, Pang, Li, Zhao, Yan, Yang, Yi, Shen, Zhonglin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637889/
https://www.ncbi.nlm.nih.gov/pubmed/19183436
http://dx.doi.org/10.1186/1471-2407-9-40