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Post-Translational Regulation of Oct4 Transcriptional Activity
Oct4 is a key component of the molecular circuitry which regulates embryonic stem cell proliferation and differentiation. It is essential for maintenance of undifferentiated, pluripotent cell populations, and accomplishes these tasks by binding DNA in multiple heterodimer and homodimer configuration...
Autores principales: | Saxe, Jonathan P., Tomilin, Alexey, Schöler, Hans R., Plath, Kathrin, Huang, Jing |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637973/ https://www.ncbi.nlm.nih.gov/pubmed/19221599 http://dx.doi.org/10.1371/journal.pone.0004467 |
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