An Antiviral Response Directed by PKR Phosphorylation of the RNA Helicase A

The double-stranded RNA-activated protein kinase R (PKR) is a key regulator of the innate immune response. Activation of PKR during viral infection culminates in phosphorylation of the α subunit of the eukaryotic translation initiation factor 2 (eIF2α) to inhibit protein translation. A broad range o...

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Detalles Bibliográficos
Autores principales: Sadler, Anthony J., Latchoumanin, Olivier, Hawkes, David, Mak, Johnson, Williams, Bryan R. G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637979/
https://www.ncbi.nlm.nih.gov/pubmed/19229320
http://dx.doi.org/10.1371/journal.ppat.1000311

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